Evaluation of the anterior scleral thickness in central serous chorioretinopathy patients by optical coherence tomography.

Author: José Ignacio Fernandez-Vigo (Spain)

Co-authors: Francisco Javier Moreno-Morillo, Hang Shi, Fernando Ly-Yang, Bárbara Burgos-Blasco, Noemí Güemes-Villahoz, Juan Donate-López

Purpose

To assess the anterior scleral thickness (AST) and to describe the presence of a visible supraciliary space (SCS) in central serous chorioretinopathy (CSCR) patients by swept-source optical coherence tomography (SS-OCT).

Setting/Venue

Hospital Clínico San Carlos, Madrid, Spain

Methods

Cross-sectional comparative study. Three groups were studied: 1) 64 eyes of 54 patients with CSCR with persistent subretinal fluid (SRF); 2) 42 fellow eyes of CSCR patients without SRF; 3) 65 eyes of 65 controls matched by age, sex and axial length (AL). The AST was measured in the temporal and nasal quadrants at 0, 1, and 2 mm from the scleral spur by SS-OCT. The presence of a visible SCS was also assessed.

Results

No differences were observed in the AST0 among the three groups (p≥ 0.665). The temporal AST1 was significantly thicker in the CSCR group (530.3 ±67.1 µm) than in the control group (505.5 ±73.9; p=0.041). Mean AST2 was also thicker in the CSCR group and the fellow eyes both for the temporal (519.4 ±89.1 µm and 519.8 ±98.5 µm respectively) and nasal quadrant (564.2 ±124.9 µm and 570.5 ±131.0 µm) than in the control group (450.1 ±76.8 and 473.3 ±111.6 µm) (all p≤0.001). A visible SCS was detected in 8 patients in CSCR eyes, in 4 fellow eyes and only in 1 control eye.

Conlusions

AST measured by SS-OCT was significantly greater in CSCR eyes than in healthy eyes. Also, a visible SCS was detected in CSCR eyes. Thus, thicker sclera in CSCR eyes could be associated with the physiopathology of this disease.

Financial Disclosure

NO

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