Macular microvascular findings in patients with Graves Ophthalmopathy: Quantitative Analysis Using Optical Coherence Tomography Angiography.

Author: El Ouafi Bouazzaoui (Tunisia)

Co-authors: Rahma Saidane, Racem Choura, Asma Khallouli, Slim Selmi, Afef Maalej, Riadh Rannen

Purpose

To evaluate retinal microvasculature in patients with Graves ophthalmopathy (GO) using optical coherence tomography angiography (OCT-A).

Setting/Venue

Department of Ophthalmology of the Military Hospital of Tunis, Tunisia.

Methods

Twenty eyes of 10 patients with inactive GO and 20 eyes of 10 age-matched healthy controls were enrolled. All included subjects underwent a comprehensive clinical assessment. OCT-A was performed using (Optovue RTVue XR Avanti, AngioVue). A 6 mm×6 macular scans with measurement of the foveal avascular zone (FAZ) and vessel densities (VD) in both superficial (SCP) and deep (DCP) capillary plexus were analyzed.

Results

The mean age was 54 ± 4.4 years in GO group and 53.5 ± 4.5 years in the control group. The VD in the SCP was significantly lower in the study group compared to the control group (52.27 ±3,45 and 54.50 ±1,48 p=0.02). The mean FAZ value was 0.285 ± 0.11 mm2 in the study group and 0.295 ± 0.13 mm2 in the control group. However, the analysis of the VD DCP and the FAZ area showed no significant differences between patients and controls (p=0.42 et p=0.61 respectively).

Conlusions

OCT-A is a non-invasive useful imaging modality in analyzing the retinal vascular network. The detection of macular vascular changes can be potentially of great help in monitoring patients with GO.

Financial Disclosure

The authors declare no conflict of interest.

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