Author: Racem Choura
Co-authors: Rahma Saidane, Khaled Khelifi, El Ouafi Bouazzaoui, Afef Maalej, Asma Khallouli
Abstract
PurposeTo investigate the relationship between retinal perfusion and retinal thickness in the macular and peripapillary areas of healthy subjects.
Setting/Venue
Department of Ophthalmology, Military Hospital of Tunis, Tunisia.
Methods
Using spectral-domain optical coherence tomography with The AngioVue™ Imaging System (RTVue XR Avanti, Optovue Inc., Fremont, CA, USA), retinal perfusion and retinal thicknesses in the macular and peripapillary areas were measured in healthy subjects. Linear correlations among these variables were analyzed.
Results
Fifty-two subjects (104 eyes) including 29 males and 23 females with a mean age of 39.5 ± 15 years were included. Linear models showed that parafoveal vessel density was significantly correlated with the inner retinal thickness (from the inner limiting membrane to the outer border of the inner nucleus layer, p = 0.02), but not with the thickness of the full retina (p = 0.13) in the parafoveal area. The foveal vessel density was negatively correlated with the inner and full foveal thicknesses (all p < 0.001). The peripapillary vessel density was positively correlated with the mean thickness of the peripapillary retinal nerve fiber layer (p = 0.003).
Conclusions
In healthy subjects, retinal vessel density was closely correlated with the thickness of the inner retinal layers in both the macular and peripapillary areas.
Financial Disclosure: No.
