Optical Coherence Tomography Angiography Findings in Tubercular Serpiginous-like Choroiditis

Author: Rahma Saidane (Tunisia)

Co-authors: Racem Choura, Asma Khallouli, Ines Féndouli, Dhouha Gouider, Afef Maalej, Riadh Rannen

Purpose

To describe and analyze the imaging features of tubercular serpiginous-like choroiditis using Optical Coherence Tomography Angiography (OCT-A).

Setting/Venue

Department of Ophthalmology of the Military Hospital of Tunis, Tunisia.

Methods

We retrospectively reviewed the files of 25 patients with Tubercular posterior uveitis. Eyes with tubercular serpiginous-like choroiditis were included in the study. Multimodal imaging was performed in all subjects: OCT-A, enhanced-depth imaging (Optovue RTVue XR Avanti) and fluorescein angiography. Morphologic features of the retinochoroidal vasculature at the sites of choroiditis lesions were analyzed on OCT-A imaging.

Results

Three eyes of 3 patients were included in the study. The en-face OCT-A images demonstrated areas of flow void beneath the complex retinal pigment epithelium-Bruch membrane layer suggestive of choriocapillaris hypoperfusion. Furthermore, areas of preserved choriocapillaris and tangled vessels were observed using OCT-A among lesions in advanced stages of healing. Compared with fluorescein angiography, the areas of choriocapillaris atrophy appeared well defined on OCT-A and correlated well with abnormalities noted on enhanced-depth imaging OCT.

Conlusions

Optical Coherence Tomography Angiography is a valuable tool in demonstrating pathological flow impairment at the level of choriocapillaris in tubercular serpiginous-like choroiditis. These findings correlate well with other imaging techniques such as fluorescein angiography.

Financial Disclosure

The authors declare no conflict of interest