Author: Laura Pavese (Italy)
Co-authors: Vittoria Murro, Dario Pasquale Mucciolo, Dario Giorgio, Daniela Quaglino, Federica Boraldi, Fabrizio Giansanti
The aim is to study retinal vessels in vivo through adaptive optics flood illumination ophthalmoscopy imaging (FIAO) in PXE patients.
University of Florence
PXE patients were recruited at Careggi Hospital (Regional Reference Center for Hereditary Retinal Dystrophies). All patients underwent complete ophthalmological examination and FIAO (rtx1; Image Eyes, Orsay, France). Adaptive optics montage imaging was done along the superior-temporal retinal vascular arcade. Wall lumen ratio (WLR) and cross-sectional area of the vascular wall (WCSA) were calculated on the basis of retinal arteriolar wall thickness (VW), lumen diameter (LD) and vessel diameter (VD) assessed by rtx1 Adaptive Optics retinal camera.
Mean arteriolar WLR is 0,21 (0,16-0,24) and mean arteriolar WCSA is 3908 (2958-5630). Arteriolar mean VW is 10,4 (9,3-11,9), mean LD 103,9 (84,8-128,4) and mean TD 125,54 (108,9-121,4). Mean venular WLR is 0,07 (0,05-0,1) and mean venular WCSA is 2593 (1713-3498). Venular mean VW is 4,18 (1,7-5,4), mean LD 145,24 (139,8-149,1) and mean TD 156,1 (151-159,9).
Our study firstly presented quantitative retinal vessels parameters using FIAO; we did not detect qualitative alterations of retinal vessels due to calcium deposits in our Pxe patients.
No financial relations