Author: Mehmet Fatih Küçük (Turkey)
Co-authors: Muhammet Kazım Erol
Purpose
Quantitative evaluation of peripapillary capillaries, optic disc capillaries, and retinal nerve fiber layer (RNFL) thickness in fellow eyes of patients with unilateral chronic central serous chorioretinopathy (CSCR).
Setting/Venue
Prospective cross-sectional, case-control study / Health Sciences University, Antalya Training and Research Hospital, Ophthalmology Clinic
Methods
The study was conducted between March 2020 and March 2021. Group 1 consisted of 28 patients with unilateral chronic CSCR and no choroidal neovascularization. Fellow eyes of these patients formed Group 2. One hundred and 2 eyes of 102 healthy control included in the study as Group3. Patient and control groups were matched in terms of age and gender. Peripapillary and macular microvascular structures were imagined with OCT-A (RTVue XR100-2 Avanti; Optovue, Inc., Fremont, CA, USA). The quantitative comparison was performed between groups
Results
There was no difference in peripapillary and inside disc area vessel densities (VD) between eyes with chronic CSCR, fellow eyes, and healthy control eyes. Similarly, there was no difference in RNFL thickness between the three groups. However, except for the foveal areas, we found that both the superficial macular and deep macular VD were lower in group1 and group 2 compared to group 3. In addition, we found that the choriocapillaris flow area decreased in group1 and group 2 compared to group 3 while the subfoveal choroidal thickness was thickened only in group 1 compared to group 3.
Conlusions
The patient with chronic CSCR in one eye had similar quantitative changes in macular vascular structures in the fellow eye compared to the control group, as well as in peripapillary vascular, optic disc vascular, and RNFL thickness. Briefly, there was no quantitative difference in peripapillary vascular structures, optic disc vascular structures, and RNFL thickness in both eyes of patients with chronic CSCR compared to the control group.
Financial Disclosure
Financial disclosure: The authors have no financial or ownership rights over a product, method, or material mentioned herein. Declaration of interest: The authors reported no conflict of interest. They are solely responsible for the content and writing of the article. Funding: The authors declare that they did not receive financial support from any foundation, public or private source for this study.
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