Contrast sensitivity in diabetics with and without retinopathy overtime

Author: Arjun Aurora (India)

Co-authors: Kamlesh Khilnani, Ajay Aurora

Purpose

To assess changes in Contrast Sensitivity (CS) in diabetics with no retinopathy (group1), with retinopathy but no macular edema (group2) and retinopathy with macular edema (group3) over a period of one year.

Setting/Venue

Prospective, non- interventional study done in the out patient department of regional referral centre

Methods

30 eyes each of patients in group 1,2, and 3 were studied over 1 year with follow up at 6 months and 12 months . All patients underwent a complete eye exam, dilated indirect ophthalmoscopy, SDOCT of macula and Contrast sensitivity using Pelli-Robson chart at 1metre. The main outcome measure was changes in CS overtime from baseline in all three groups

Results

The Contrast sensitivity in-group 1: 1.49+/- 0.19 at baseline, 1.47+/- 0.21 at 6 months, and 1.46+/- 0.21 at 12 months. Contrast sensitivity in-group 2: 1.46+/- 0.15 at baseline, 1.47+/- 0.15 at 6 months, and 1.37+/- 0.15 at 12 months. Contrast sensitivity in-group 3: at baseline, 6 months, and 12 months was 1.21+/- 0.23, 1.20+/- 0.22, 1.19+/- 0.22. On comparing groups 1 with 3 and 2 with 3, significance was noted at all 3 time zones.

Conlusions

There was no deterioration in CS over baseline during the 1-year follow-up in Group 1 and at 6 months in-group 2. However, deterioration in CS became significant in-group 2 at 12 months. Interestingly, CS did not deteriorate significantly overtime within group 3 but was significantly lower when comparing group 3 with either 2 or 1.

Financial Disclosure

None