Features of the natural history of lamellar macular holes with epiretinal proliferation.

Author: Konstantin Zhogolev (Russian Federation)

Co-authors: Irina Panova

Purpose

To establish the features of the course and the possibilities of the SLO in the diagnosis of lamellar macular holes with the presence of epiretinal proliferation.

Setting/Venue

The question of natural history of LMH (favorable or progressive) remains controversial to this day. It is relevant to study the role of epiretinal proliferation (EP) on the natural course of the disease, as well as the value of the method of scanning laser ophthalmoscopy (SLO) in the diagnosis of EP.

Methods

Clinical and instrumental monitoring was carried out in 48 patients with LMH in two groups: with the presence of EP (27 patients) and its absence (21 patients). The follow-up period was 15.9 ± 2.3 months. The dynamics of the best corrected visual acuity (BCVA), mean retinal sensitivity (MRS) of the retina in 2 and 4 degree zones, subjective complaints were assessed; according to OCT data - the main morphometric and morphostructural parameters of the retina. SLO was performed in 21 patients with LMH with the presence of EP.

Results

Patients with LMH and presence of EP had an initial lower BCVA, as well as according to OCT, disruption of the ellipsoid zone and the presence of a central foveal bump (37% and 22.2% of patients, respectively). During the follow-up, patients with EP showed an increase in subjective complaints, a statistically significant decrease in the retinal MRS in the 2-degree zone, and a decrease of the minimum retinal thickness. In all cases, the SLO made it possible to visualize the EP.

Conlusions

LMH with EP are characterized by an unfavorable course, which is confirmed by a decrease in functional parameters and a deterioration in anatomical parameters.

Financial Disclosure

No

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