Functional and anatomical prognostic biomarkers by swept source optical coherence tomography after epiretinal membrane surgery

Author: Maria Parra (Colombia)

Co-authors: Juan David Arias, Eduardo J. Viteri, Carlos M. Rangel, Ronald M Sanchez-Avila

Purpose

To determine the visual and anatomical prognostic biomarkers in patients with epiretinal (ERM) treated surgically.

Setting/Venue

International FOSCAL, Floridablanca, Colombia.

Methods

Retrospective analytical cohort study. In patients treated with PPV and ERM removal, a correlation was established between the preoperative visual acuity (VA) and preoperative swept-source optical coherence tomography (SS-OCT) variables with the best-corrected VA change (BCVA) and the reduction in average macular thickness (AMT) post-operatively.

Results

A total of 168 eyes of 138 patients with ERM were evaluated, 71 eyes were treated with PPV and ERM removal. The mean follow-up time was 5.25 months (SD ± 7.8) and the mean age was 71.9 years (SD ± 7.2). The preoperative BCVA was LogMAR 0.57 (Snellen: 20/70), with a postoperative BCVA of LogMAR 0.39 (Snellen: 20/50). The EMP was reduced from 326.3μm (SD ± 161.2) to 307.2μm (SD ± 153.45). The variable with the highest correlation with the change in BCVA was preoperative BCVA (p <0.05). The variables that showed a positive correlation with the reduction of AMT were preoperative BCVA (p <0.05), ERM stage 1 (p = 0.022) and the presence of internal foveal ectopic layers (EIFLs) (p = 0.007).

Conlusions

Preoperative BCVA, ERM stage 1 and the presence of EIFLs were correlated with a change in BCVA and EMP reduction after surgical management in patients with ERM.

Financial Disclosure

Juan D. Arias: Topcon consultant

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