Author: Irini Chatziralli (Greece)
Co-authors: Alexandros Chatzirallis, Agoritsa Varaklioti, Panagiotis Theodossiadis, Theodoros Sergentanis
The purpose of this study was to evaluate health-related quality of life in patients with retinal vein occlusion (RVO) and investigate the possible risk factors for poor quality of life in RVO patients.
2nd Department of Ophthalmology, University of Athens, Athens, Greece
Participants in the study were 67 patients with RVO, 42 male and 25 female, mean-aged 73.1±10.9 years, and 70 controls adjusted for sex and age. Demographic data, lifestyle factors and medical history were recorded. All patients underwent best-corrected visual acuity measurement, dilated fundoscopy and optical coherence tomography. All participants completed two questionnaires assessing quality of life (EQ-5D, NEI VFQ-25). Risk factors for health-related quality of life in RVO patients were investigated.
Patients with RVO presented significantly lower composite score for VFQ-25 compared to controls (74.1±3.8 vs. 91.7±3.9 for patients and controls respectively, p<0.001). In addition, RVO patients had significantly lower EQ-5D Index score compared to controls (0.88±0.15 vs. 0.92±0.12 for patients and controls respectively, p=0.043). Risk factors associated with quality of life in patients with RVO were found the alcohol consumption, the presence of thyroidopathy, coagulation disorders, visual acuity in the eye with RVO, central retinal thickness, the type of edema, the presence of ischemia and the condition of external limiting membrane. In multivariate analysis, only alcohol consumption and visual acuity in the eye with RVO were found to be independent risk factors, affecting quality of life in RVO patients.
Patients with RVO presented lower quality of life in comparison with controls. Potential risk factors should be taken into account and their early detection may improve quality of life in such patients and lead to targeted health politics.