Author: Lidia Remolí Sargues (Spain)
Co-authors: Clara Monferrer Adsuara, Verónica Castro Navarro, Catalina Navarro Palop, Javier Montero Hernández, Enrique Cervera Taulet
Purpose
There is a lack of information on quantitative parameters of optical coherence tomography angiography (OCTA) in cases of chorioretinal folds (CRF). The aim of this study was to compare OCTA retinal and choriocapillaris (CC) vessel density (VD) between normal subjects and patients with CRF secondary to primary hyperopia.
Setting/Venue
We conducted an observational retrospective study in the Retina service at the Consorcio Hospital General Universitario of Valencia, Spain. A total of 16 eyes of 8 patients were recruited (8 eyes with CRF and 8 control eyes).
Methods
Data on best-corrected visual acuity (BCVA), refractive error, central macular thickness (CMT), central subfoveal thickness (CST), and OCTA findings (VD and foveal avascular zone (FAZ) area in superficial capillary plexus (SCP), middle capillary plexus (MCP), and deep capillary plexus (DCP), and VD in CC) were recorded in each eye.
Results
Compared with control group, CRF group showed decreased VD in the foveal region of SCP and MCP (p value 0,003 and 0,001), and increased VD in nasal region of SCP and MCP (p value 0,02 and 0,001), and in parafoveal area of MCP (p value 0,005). No differences were found in DCP and CC layers. Furthermore, we observed an enlargement of FAZ in CRF group at SCP and MCP slabs (p value <0,001 and 0,015). Respect to optical coherence tomography parameters, we demonstrated a thicker choroid in the CRF group (p value 0,002).
Conlusions
To the best of our knowledge, our study quantified VD of retinal capillary plexus and CC in a group of patients with a diagnosis of CRF secondary to primary hyperopia. We did not find a significant decrease of VD in DCP and CC, suggesting that there is no vascular involvement, but further studies with bigger population are needed to confirm this hypothesis.
Financial Disclosure
None
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