Author: Mohaimen Al-Zubaidy (United Kingdom)
Co-authors: Mohaimen Al-Zubaidy, Anna Song, Mariantonia Ferrara, David Steel
Purpose
RRD has an incidence of 0.01%-0.02% in the general population. Although the incidence of RRD is highly related to age, it is currently unclear as to whether age itself has an effect on the characteristics of the RRD, and whether this impacts the surgical outcome. The aim of this study was to analyse the effect of age on the clinical phenotype, and anatomical and functional outcomes in a large prospectively collected cohort of patients.
Setting/Venue
Database study of over 50 surgeons in the UK and Europe.
Methods
Data from 8133 patients with RRDs who had undergone surgical intervention between the ages of 16 and 100 years, from 2015-2019. Data was entered prospectively on a variety of baseline and operative variables, with postoperative outcome entered at least 2 months after surgery. The effect of age was analysed in 7 age bands (below 31, 31-40, 41-50, 51-60, 61-70, 71-80 and above 80 years) on all variables.
Results
The mean age, and highest incidence of RRD was at 59 years old with 63% of the participants being male. The male predominance extended across all age groups, only reducing in the over 80s age cohort. All baseline variables (presenting visual acuity, lens status, vitreous attachment, vitreous haemorrhage, refraction, RD extent and distribution, foveal attachment, fellow eye RD) were strongly related to age (p all<0.001). Baseline visual acuity worsened, macular involvement and RD extent, and PVR prevalence increased, whilst fellow eye involvement reduced with age. The incidence of pseudophakic RD increased with age. The presence of posterior vitreous detachment and refraction also increased with age. The presence of vitreous haemorrhage was greatest in the 51-60 age group and reduced at the extremes of age. The proportion with inferior retinal breaks decreased, whilst those with superior breaks increased with age. The proportion of U shaped breaks peaked between 61-70 years and reduced at the extremes of age. Both anatomical and functional outcomes were also strongly related to age. In macular involving RRD visual outcome peaked at 41-50 years and anatomical success peaked at 51-60 years but both reduced towards the extremes of age.
Conlusions
The features and outcomes of RRD are highly related to age, and should be considered in studies and audits evaluating novel interventions and agents.
Financial Disclosure
N/A
Comments
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