The frequency and structure of vascular retinal pathology in women after preeclampsia and in its combination with chronic arterial hypertension

Author: Oleg Kolenko (Russian Federation)

Co-authors: Evgenii Sorokin, Anastasia Fil

Purpose

To study the frequency and structure of vascular retinal pathology in women after preeclampsia (PE) and in its combination with chronic arterial hypertension (AH).

Setting/Venue

The work was performed in the S. Fyodorov Eye Microsurgery Federal State Institution, Khabarovsk, Russia

Methods

An analysis of 231 perinatal records of women with various variants of the course of pregnancy was carried out. 4 groups were formed depending on the variant of the course of pregnancy. 1st main group - PE against the background of chronic hypertension (47 people). 2nd main group - pregnancy complicated by PE (48 people). 1st comparison group - pregnancy complicated by gestational hypertension (50 people). 2nd comparison group - edema and proteinuria without hypertension (36 people). The control group consisted of 50 women with physiological pregnancy. The age of women in the general population varied from 28 to 51 years, averaging 39±6.2 years. All of them were invited for examination and detection of vascular retinal pathology 6–12 years after childbirth.

Results

The formation of vascular retinal pathology in 19 out of 28 women in the general population occurred at the age of 38–40 years (68%). The frequency of vascular retinal pathology in the 1st and 2nd main groups was the highest - 21% and 25% (10 and 12 women, respectively). This turned out to be statistically significantly higher than similar indicators in the control group, as well as in the 1st and 2nd comparison groups (4%, 4%, 6% respectively, p<0.01). In the 1st main group: in 6 people vascular retinal pathology was represented by occlusion of the branch of the central retinal vein (OBCRV), in 3 people - OBCRV which was complicated by proliferative retinopathy, one woman was diagnosed with occlusion of the central retinal artery. In the 2nd main group: in 7 people OBCRV was detected, in 5 women - OBCRV complicated by proliferative retinopathy. In the control group, 1st and 2nd comparison groups 2 cases of OBCRV were detected.

Conlusions

The highest incidence of vascular retinal pathology was found in the 1st and 2nd main groups, its indicators were statistically significantly higher relative to the control group, 1st and 2nd comparison groups, p<0.01. The data obtained objectively testified to the priority role of PE and PE against the background of chronic hypertension in the formation of vascular retinal pathology in the long-term postnatal period.

Financial Disclosure

no companies