Author: Evita Evangelia Christou (Greece)
Co-authors: Evita Evangelia Christou, Paraskevas Zafeiropoulos, Eleni Bagli, Andreas Katsanos, Ioannis Asproudis, Maria Stefaniotou
Purpose
To assess the retinal function of eyes that have undergone successful pars plana vitrectomy (PPV) with silicone oil (SO) tamponade for rhegmatogenous retinal detachment (RRD) with macular involvement (“macula-off”).
Setting/Venue
University Hospital of Ioannina, Ioannina, Greece
Methods
Ten eyes of 10 patients were included in this prospective study. Full-field electroretinogram (ffERG) and multifocal electroretinogram (mfERG) were recorded one day prior to SO removal and 3 days following SO removal. The amplitude and implicit time of P1 and N1 waves were evaluated. The patients’ fellow eyes were used as controls.
Results
With ffERG, treated eyes had significantly lower P1 and N1 wave amplitudes before SO removal compared to amplitudes after SO removal (P1 and N1: p≤0.01), and compared to controls (P1 and N1: p≤0.01). With mfERG, treated eyes had significantly lower N1 wave amplitudes in the central R1+R2+R3 rings and in each of R4 and R5 peripheral rings of the macular area before SO compared to the amplitudes after SO removal (R1+R2+R3, R4, R5, R6: p≤0.05), and compared to controls (R1+R2+R3, R4, R5, R6: p≤0.01). P1 and N1 wave implicit time did not differ significantly in eyes before SO removal compared to those after SO removal and the control in both ffERG and mf ERG (P1 and N1: p≥0.05).
Conlusions
ffERG and mfERG may be used for the evaluation of retinal function in macula-off RRD eyes with SO tamponade. The retinal response density in electroretinogram increased following the removal of intravitreal SO, indicating an amelioration of the electrical activity of the retina and the macular area.
Financial Disclosure
None
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